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Cleaved Delta like 1 intracellular domain regulates neural development via Notch signal-dependent and -independent pathways

Notch-Delta signaling regulates many developmental processes, including tissue homeostasis and maintenance of stem cells. Upon interaction of juxtaposed cells via Notch and Delta proteins, intracellular domains of both transmembrane proteins are cleaved and translocate to the nucleus. Notch intracel...

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Detalles Bibliográficos
Autores principales: Okubo, Yusuke, Ohtake, Fumiaki, Igarashi, Katsuhide, Yasuhiko, Yukuto, Hirabayashi, Yoko, Saga, Yumiko, Kanno, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513606/
https://www.ncbi.nlm.nih.gov/pubmed/34519339
http://dx.doi.org/10.1242/dev.193664