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Optimization of translation enhancing element use to increase protein expression in a vaccinia virus system

Since the successful use of vaccinia virus (VACV) in the immunization strategies to eliminate smallpox, research has been focused on the development of recombinant VACV strains expressing proteins from various pathogens. Attempts at decreasing the side effects associated with exposure to recombinant...

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Detalles Bibliográficos
Autores principales: Richard Jr., Harold B., Minder, Stephanie, Sidhu, Amandeep, Juba, Amber N., Jancovich, James K., Jacobs, Bertram L., Wellensiek, Brian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513643/
https://www.ncbi.nlm.nih.gov/pubmed/34382930
http://dx.doi.org/10.1099/jgv.0.001624