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CRISPR-Mediated Transcriptional Repression in Toxoplasma gondii

Tools for tuning endogenous gene expression are key to determining the genetic basis of diverse cellular phenotypes. Although synthetic regulatable promoters are available in Toxoplasma, scalable methods for targeted and combinatorial downregulation of gene expression—like RNA interference—have yet...

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Detalles Bibliográficos
Autores principales: Markus, Benedikt M., Boydston, Elizabeth A., Lourido, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513686/
https://www.ncbi.nlm.nih.gov/pubmed/34643425
http://dx.doi.org/10.1128/mSphere.00474-21