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Serum Testosterone to Androstenedione Ratio Predicts Metabolic Health in Normal-Weight Polycystic Ovary Syndrome Women

CONTEXT: Increased aldo-keto reductase 1C3 (AKR1C3)-mediated conversion of androstenedione (A4) to testosterone (T) promotes lipid storage in subcutaneous (SC) abdominal adipose in overweight/obese polycystic ovary syndrome (PCOS) women. OBJECTIVE: This work examines whether an elevated serum T/A4 r...

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Detalles Bibliográficos
Autores principales: Dumesic, Daniel A, Tulberg, Ayli, McNamara, Megan, Grogan, Tristan R, Abbott, David H, Naik, Rajanigandha, Lu, Gwyneth, Chazenbalk, Gregorio D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513761/
https://www.ncbi.nlm.nih.gov/pubmed/34661039
http://dx.doi.org/10.1210/jendso/bvab158