Photocrosslinked Bioreducible Polymeric Nanoparticles for Enhanced Systemic siRNA Delivery as Cancer Therapy

Clinical translation of polymer-based nanocarriers for systemic delivery of RNA has been limited due to poor colloidal stability in the blood stream and intracellular delivery of the RNA to the cytosol. To address these limitations, this study reports a new strategy incorporating photocrosslinking o...

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Detalles Bibliográficos
Autores principales: Karlsson, Johan, Tzeng, Stephany Y., Hemmati, Shayan, Luly, Kathryn M., Choi, Olivia, Rui, Yuan, Wilson, David R., Kozielski, Kristen L., Quiñones-Hinojosa, Alfredo, Green, Jordan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513781/
https://www.ncbi.nlm.nih.gov/pubmed/34650390
http://dx.doi.org/10.1002/adfm.202009768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513781/
https://www.ncbi.nlm.nih.gov/pubmed/34650390
http://dx.doi.org/10.1002/adfm.202009768

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