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Photocrosslinked Bioreducible Polymeric Nanoparticles for Enhanced Systemic siRNA Delivery as Cancer Therapy
Clinical translation of polymer-based nanocarriers for systemic delivery of RNA has been limited due to poor colloidal stability in the blood stream and intracellular delivery of the RNA to the cytosol. To address these limitations, this study reports a new strategy incorporating photocrosslinking o...
Autores principales: | Karlsson, Johan, Tzeng, Stephany Y., Hemmati, Shayan, Luly, Kathryn M., Choi, Olivia, Rui, Yuan, Wilson, David R., Kozielski, Kristen L., Quiñones-Hinojosa, Alfredo, Green, Jordan J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513781/ https://www.ncbi.nlm.nih.gov/pubmed/34650390 http://dx.doi.org/10.1002/adfm.202009768 |
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