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Induction of IL-12p40 and type 1 immunity by Toxoplasma gondii in the absence of the TLR-MyD88 signaling cascade

Toxoplasma gondii is an orally acquired pathogen that induces strong IFN-γ based immunity conferring protection but that can also be the cause of immunopathology. The response in mice is driven in part by well-characterized MyD88-dependent signaling pathways. Here we focus on induction of less well...

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Detalles Bibliográficos
Autores principales: Snyder, Lindsay M., Doherty, Claire M., Mercer, Heather L., Denkers, Eric Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513874/
https://www.ncbi.nlm.nih.gov/pubmed/34597344
http://dx.doi.org/10.1371/journal.ppat.1009970