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Cooperative stabilisation of 14-3-3σ protein–protein interactions via covalent protein modification

14-3-3 proteins are an important family of hub proteins that play important roles in many cellular processes via a large network of interactions with partner proteins. Many of these protein–protein interactions (PPI) are implicated in human diseases such as cancer and neurodegeneration. The stabilis...

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Detalles Bibliográficos
Autores principales: Falcicchio, Marta, Ward, Jake A., Chothia, Sara Y., Basran, Jaswir, Mohindra, Alisha, Macip, Salvador, Roversi, Pietro, Doveston, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513901/
https://www.ncbi.nlm.nih.gov/pubmed/34745529
http://dx.doi.org/10.1039/d1sc02120f