Selective functionalization of the 1H-imidazo[1,2-b]pyrazole scaffold. A new potential non-classical isostere of indole and a precursor of push–pull dyes

We report the selective functionalization of the 1H-imidazo[1,2-b]pyrazole scaffold using a Br/Mg-exchange, as well as regioselective magnesiations and zincations with TMP-bases (TMP = 2,2,6,6-tetramethylpiperidyl), followed by trapping reactions with various electrophiles. In addition, we report a...

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Detalles Bibliográficos
Autores principales: Schwärzer, Kuno, Rout, Saroj K., Bessinger, Derya, Lima, Fabio, Brocklehurst, Cara E., Karaghiosoff, Konstantin, Bein, Thomas, Knochel, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513920/
https://www.ncbi.nlm.nih.gov/pubmed/34745530
http://dx.doi.org/10.1039/d1sc04155j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513920/
https://www.ncbi.nlm.nih.gov/pubmed/34745530
http://dx.doi.org/10.1039/d1sc04155j

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