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Single-Cell Analysis of the Multicellular Ecosystem in Viral Carcinogenesis by HTLV-1

Premalignant clonal expansion of human T-cell leukemia virus type-1 (HTLV-1)–infected cells occurs before viral carcinogenesis. Here we characterize premalignant cells and the multicellular ecosystem in HTLV-1 infection with and without adult T-cell leukemia/lymphoma (ATL) by genome sequencing and s...

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Detalles Bibliográficos
Autores principales: Koya, Junji, Saito, Yuki, Kameda, Takuro, Kogure, Yasunori, Yuasa, Mitsuhiro, Nagasaki, Joji, McClure, Marni B., Shingaki, Sumito, Tabata, Mariko, Tahira, Yuki, Akizuki, Keiichi, Kamiunten, Ayako, Sekine, Masaaki, Shide, Kotaro, Kubuki, Yoko, Hidaka, Tomonori, Kitanaka, Akira, Nakano, Nobuaki, Utsunomiya, Atae, Togashi, Yosuke, Ogawa, Seishi, Shimoda, Kazuya, Kataoka, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514013/
https://www.ncbi.nlm.nih.gov/pubmed/34661162
http://dx.doi.org/10.1158/2643-3230.BCD-21-0044