Copy-scAT: Deconvoluting single-cell chromatin accessibility of genetic subclones in cancer

Single-cell epigenomic assays have tremendous potential to illuminate mechanisms of transcriptional control in functionally diverse cancer cell populations. However, application of these techniques to clinical tumor specimens has been hampered by the current inability to distinguish malignant from n...

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Detalles Bibliográficos
Autores principales: Nikolic, Ana, Singhal, Divya, Ellestad, Katrina, Johnston, Michael, Shen, Yaoqing, Gillmor, Aaron, Morrissy, Sorana, Cairncross, J. Gregory, Jones, Steven, Lupien, Mathieu, Chan, Jennifer A., Neri, Paola, Bahlis, Nizar, Gallo, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514091/
https://www.ncbi.nlm.nih.gov/pubmed/34644115
http://dx.doi.org/10.1126/sciadv.abg6045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514091/
https://www.ncbi.nlm.nih.gov/pubmed/34644115
http://dx.doi.org/10.1126/sciadv.abg6045

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