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Repression of Osmr and Fgfr1 by miR-1/133a prevents cardiomyocyte dedifferentiation and cell cycle entry in the adult heart

Dedifferentiation of cardiomyocytes is part of the survival program in the remodeling myocardium and may be essential for enabling cardiomyocyte proliferation. In addition to transcriptional processes, non-coding RNAs play important functions for the control of cell cycle regulation in cardiomyocyte...

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Detalles Bibliográficos
Autores principales: Valussi, Melissa, Besser, Johannes, Wystub-Lis, Katharina, Zukunft, Sven, Richter, Manfred, Kubin, Thomas, Boettger, Thomas, Braun, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514096/
https://www.ncbi.nlm.nih.gov/pubmed/34644107
http://dx.doi.org/10.1126/sciadv.abi6648