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Insertional activation of STAT3 and LCK by HIV-1 proviruses in T cell lymphomas

Retroviruses cause cancers in animals by integrating in or near oncogenes. Although HIV-1 infection increases the risk of cancer, most of the risk is associated with immunodeficiency and coinfection by oncogenic virus (Epstein-Barr virus, Kaposi sarcoma herpesvirus, and human papillomavirus). HIV-1...

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Detalles Bibliográficos
Autores principales: Mellors, John W., Guo, Shuang, Naqvi, Asma, Brandt, Leah D., Su, Ling, Sun, Zhonghe, Joseph, Kevin W., Demirov, Dimiter, Halvas, Elias K., Butcher, Donna, Scott, Beth, Hamilton, Aaron, Heil, Marintha, Karim, Baktiar, Wu, Xiaolin, Hughes, Stephen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514100/
https://www.ncbi.nlm.nih.gov/pubmed/34644108
http://dx.doi.org/10.1126/sciadv.abi8795