Cargando…
Insertional activation of STAT3 and LCK by HIV-1 proviruses in T cell lymphomas
Retroviruses cause cancers in animals by integrating in or near oncogenes. Although HIV-1 infection increases the risk of cancer, most of the risk is associated with immunodeficiency and coinfection by oncogenic virus (Epstein-Barr virus, Kaposi sarcoma herpesvirus, and human papillomavirus). HIV-1...
Autores principales: | Mellors, John W., Guo, Shuang, Naqvi, Asma, Brandt, Leah D., Su, Ling, Sun, Zhonghe, Joseph, Kevin W., Demirov, Dimiter, Halvas, Elias K., Butcher, Donna, Scott, Beth, Hamilton, Aaron, Heil, Marintha, Karim, Baktiar, Wu, Xiaolin, Hughes, Stephen H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514100/ https://www.ncbi.nlm.nih.gov/pubmed/34644108 http://dx.doi.org/10.1126/sciadv.abi8795 |
Ejemplares similares
-
HIV-1 Vpr induces ciTRAN to prevent transcriptional repression of the provirus
por: Bhardwaj, Vipin, et al.
Publicado: (2023) -
Deep Sequencing Analysis of Individual HIV-1 Proviruses Reveals Frequent Asymmetric Long Terminal Repeats
por: Joseph, Kevin W., et al.
Publicado: (2022) -
HIV infected CD4+ T cell clones are more stable than uninfected clones during long-term antiretroviral therapy
por: Guo, Shuang, et al.
Publicado: (2022) -
Unique amphipathic α helix drives membrane insertion and enzymatic activity of ATG3
por: Nishimura, Taki, et al.
Publicado: (2023) -
The D614G mutation redirects SARS-CoV-2 spike to lysosomes and suppresses deleterious traits of the furin cleavage site insertion mutation
por: Guo, Chenxu, et al.
Publicado: (2022)