NON-VIRAL REPROGRAMMING OF HUMAN NUCLEUS PULPOSUS CELLS WITH FOXF1 VIA EXTRACELLULAR VESICLE DELIVERY: AN IN VITRO AND IN VIVO STUDY

Intervertebral disc (IVD) degeneration is characterized by decreased cellularity and proteoglycan synthesis and increased inflammation, catabolism, and neural/vascular ingrowth. Regenerative methods for IVD degeneration are largely cell-therapy-based or involve viral vectors, which are associated wi...

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Detalles Bibliográficos
Autores principales: Tang, S., Salazar-Puerta, A., Richards, J., Khan, S., Hoyland, J.A., Gallego-Perez, D., Walter, B., Higuita-Castro, N., Purmessur, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514169/
https://www.ncbi.nlm.nih.gov/pubmed/33465243
http://dx.doi.org/10.22203/eCM.v041a07

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514169/
https://www.ncbi.nlm.nih.gov/pubmed/33465243
http://dx.doi.org/10.22203/eCM.v041a07

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