Development and Dynamics of Cytomegalovirus UL97 Ganciclovir Resistance Mutations in Transplant Recipients Detected by Next-Generation Sequencing

BACKGROUND: (Val)ganciclovir resistance mutations in CMV UL97 (UL97-GCV-R) complicate anti-CMV therapy in recipients of solid organ and hematopoietic stem cell transplants, but comprehensive data on prevalence, emergence, and outcome are scarce. METHODS: Using next-generation sequencing (NGS; Illumi...

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Detalles Bibliográficos
Autores principales: Lodding, Isabelle P, Jørgensen, Mette, Bennedbæk, Marc, Kirkby, Nikolai, Naegele, Klaudia, Gustafsson, Finn, Perch, Michael, Rasmussen, Allan, Sengeløv, Henrik, Sørensen, Søren S, Hirsch, Hans H, Lundgren, Jens D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Major Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514173/
https://www.ncbi.nlm.nih.gov/pubmed/34660835
http://dx.doi.org/10.1093/ofid/ofab462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514173/
https://www.ncbi.nlm.nih.gov/pubmed/34660835
http://dx.doi.org/10.1093/ofid/ofab462

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