Multifunctional Antibodies Are Induced by the RTS,S Malaria Vaccine and Associated With Protection in a Phase 1/2a Trial

BACKGROUND: RTS,S is the leading malaria vaccine candidate but only confers partial efficacy against malaria in children. RTS,S is based on the major Plasmodium falciparum sporozoite surface antigen, circumsporozoite protein (CSP). The induction of anti-CSP antibodies is important for protection; ho...

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Detalles Bibliográficos
Autores principales: Kurtovic, Liriye, Atre, Tanmaya, Feng, Gaoqian, Wines, Bruce D, Chan, Jo-Anne, Boyle, Michelle J, Drew, Damien R, Hogarth, P Mark, Fowkes, Freya J I, Bergmann-Leitner, Elke S, Beeson, James G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514181/
https://www.ncbi.nlm.nih.gov/pubmed/32236404
http://dx.doi.org/10.1093/infdis/jiaa144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514181/
https://www.ncbi.nlm.nih.gov/pubmed/32236404
http://dx.doi.org/10.1093/infdis/jiaa144

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