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Noninvasive Determination of CMV Serostatus From Dried Buccal Swab Samples: Assay Development, Validation, and Application to 1.2 Million Samples

BACKGROUND: Buccal swab sampling constitutes an attractive noninvasive alternative to blood drawings for antibody serostatus assays. Here we describe a method to determine the cytomegalovirus immunoglobulin G (CMV IgG) serostatus from dried buccal swab samples. METHODS: Upon solubilization, CMV IgG...

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Detalles Bibliográficos
Autores principales: Behrens, Geoffrey A, Brehm, Michael, Groß, Rita, Heider, Jana, Sauter, Jürgen, Baier, Daniel M, Wehde, Tatjana, Castriciano, Santina, Schmidt, Alexander H, Lange, Vinzenz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514182/
https://www.ncbi.nlm.nih.gov/pubmed/32052845
http://dx.doi.org/10.1093/infdis/jiaa067