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Monocyte-derived transcriptome signature indicates antibody-dependent cellular phagocytosis as a potential mechanism of vaccine-induced protection against HIV-1

A gene signature was previously found to be correlated with mosaic adenovirus 26 vaccine protection in simian immunodeficiency virus and simian-human immunodeficiency virus challenge models in non-human primates. In this report, we investigated the presence of this signature as a correlate of reduce...

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Detalles Bibliográficos
Autores principales: Shangguan, Shida, Ehrenberg, Philip K, Geretz, Aviva, Yum, Lauren, Kundu, Gautam, May, Kelly, Fourati, Slim, Nganou-Makamdop, Krystelle, Williams, LaTonya D, Sawant, Sheetal, Lewitus, Eric, Pitisuttithum, Punnee, Nitayaphan, Sorachai, Chariyalertsak, Suwat, Rerks-Ngarm, Supachai, Rolland, Morgane, Douek, Daniel C, Gilbert, Peter, Tomaras, Georgia D, Michael, Nelson L, Vasan, Sandhya, Thomas, Rasmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514236/
https://www.ncbi.nlm.nih.gov/pubmed/34533134
http://dx.doi.org/10.7554/eLife.69577