Human embryo polarization requires PLC signaling to mediate trophectoderm specification

Apico-basal polarization of cells within the embryo is critical for the segregation of distinct lineages during mammalian development. Polarized cells become the trophectoderm (TE), which forms the placenta, and apolar cells become the inner cell mass (ICM), the founding population of the fetus. The...

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Detalles Bibliográficos
Autores principales: Zhu, Meng, Shahbazi, Marta, Martin, Angel, Zhang, Chuanxin, Sozen, Berna, Borsos, Mate, Mandelbaum, Rachel S, Paulson, Richard J, Mole, Matteo A, Esbert, Marga, Titus, Shiny, Scott, Richard T, Campbell, Alison, Fishel, Simon, Gradinaru, Viviana, Zhao, Han, Wu, Keliang, Chen, Zi-Jiang, Seli, Emre, de los Santos, Maria J, Zernicka Goetz, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514238/
https://www.ncbi.nlm.nih.gov/pubmed/34569938
http://dx.doi.org/10.7554/eLife.65068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514238/
https://www.ncbi.nlm.nih.gov/pubmed/34569938
http://dx.doi.org/10.7554/eLife.65068

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