Cargando…

TERT promoter mutation is an objective clinical marker for disease progression in chondrosarcoma

Chondrosarcomas are the second most common malignant bone tumor. Activating promoter mutations in telomerase reverse transcriptase (TERT) was recently described by us and others as a frequent mutation in high-grade chondrosarcoma. In this study, we investigate the prognostic significance of TERT pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yifan, Chen, Yi, Yang, Chen, Seger, Nelly, Hesla, Asle C., Tsagkozis, Panagiotis, Larsson, Olle, Lin, Yingbo, Haglund, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514332/
https://www.ncbi.nlm.nih.gov/pubmed/34108637
http://dx.doi.org/10.1038/s41379-021-00848-0