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Frequent PIK3CA mutations in eutopic endometrium of patients with ovarian clear cell carcinoma

Recent studies have reported cancer-associated mutations in normal endometrium. Mutations in eutopic endometrium may lead to endometriosis and endometriosis-associated ovarian cancer. We investigated PIK3CA mutations (PIK3CAm) for three hotspots (E542K, E545K, H1047R) in eutopic endometrium in patie...

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Detalles Bibliográficos
Autores principales: Murakami, Kosuke, Kanto, Akiko, Sakai, Kazuko, Miyagawa, Chiho, Takaya, Hisamitsu, Nakai, Hidekatsu, Kotani, Yasushi, Nishio, Kazuto, Matsumura, Noriomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514336/
https://www.ncbi.nlm.nih.gov/pubmed/34172890
http://dx.doi.org/10.1038/s41379-021-00861-3