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Frequent PIK3CA mutations in eutopic endometrium of patients with ovarian clear cell carcinoma
Recent studies have reported cancer-associated mutations in normal endometrium. Mutations in eutopic endometrium may lead to endometriosis and endometriosis-associated ovarian cancer. We investigated PIK3CA mutations (PIK3CAm) for three hotspots (E542K, E545K, H1047R) in eutopic endometrium in patie...
Autores principales: | Murakami, Kosuke, Kanto, Akiko, Sakai, Kazuko, Miyagawa, Chiho, Takaya, Hisamitsu, Nakai, Hidekatsu, Kotani, Yasushi, Nishio, Kazuto, Matsumura, Noriomi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514336/ https://www.ncbi.nlm.nih.gov/pubmed/34172890 http://dx.doi.org/10.1038/s41379-021-00861-3 |
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