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Structural basis of human transcription–DNA repair coupling

Transcription-coupled DNA repair removes bulky DNA lesions from the genome(1,2) and protects cells against ultraviolet (UV) irradiation(3). Transcription-coupled DNA repair begins when RNA polymerase II (Pol II) stalls at a DNA lesion and recruits the Cockayne syndrome protein CSB, the E3 ubiquitin...

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Detalles Bibliográficos
Autores principales: Kokic, Goran, Wagner, Felix R., Chernev, Aleksandar, Urlaub, Henning, Cramer, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514338/
https://www.ncbi.nlm.nih.gov/pubmed/34526721
http://dx.doi.org/10.1038/s41586-021-03906-4