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Systemic mesalazine treatment prevents spontaneous skin fibrosis in PLK2-deficient mice

Skin fibrosis is a complex biological remodeling process occurring in disease like systemic sclerosis, morphea, or eosinophilic fasciitis. Since the knowledge about the underlying pathomechanisms is still incomplete, there is currently no therapy, which prevents or reverses skin fibrosis sufficientl...

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Detalles Bibliográficos
Autores principales: Newe, Manja, Kant, Theresa A., Hoffmann, Maximilian, Rausch, Johanna S. E., Winter, Luise, Künzel, Karolina, Klapproth, Erik, Günther, Claudia, Künzel, Stephan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514377/
https://www.ncbi.nlm.nih.gov/pubmed/34410453
http://dx.doi.org/10.1007/s00210-021-02135-w