Cargando…
Systemic mesalazine treatment prevents spontaneous skin fibrosis in PLK2-deficient mice
Skin fibrosis is a complex biological remodeling process occurring in disease like systemic sclerosis, morphea, or eosinophilic fasciitis. Since the knowledge about the underlying pathomechanisms is still incomplete, there is currently no therapy, which prevents or reverses skin fibrosis sufficientl...
Autores principales: | Newe, Manja, Kant, Theresa A., Hoffmann, Maximilian, Rausch, Johanna S. E., Winter, Luise, Künzel, Karolina, Klapproth, Erik, Günther, Claudia, Künzel, Stephan R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514377/ https://www.ncbi.nlm.nih.gov/pubmed/34410453 http://dx.doi.org/10.1007/s00210-021-02135-w |
Ejemplares similares
-
Repurposing mesalazine against cardiac fibrosis in vitro
por: Hoffmann, Maximilian, et al.
Publicado: (2020) -
Genetic Deletion of Polo-Like Kinase 2 Induces a Pro-Fibrotic Pulmonary Phenotype
por: Kant, Theresa A., et al.
Publicado: (2021) -
Investigation of mesalazine as an antifibrotic drug following myocardial infarction in male mice
por: Künzel, Stephan R., et al.
Publicado: (2023) -
Modeling atrial fibrosis in vitro—Generation and characterization of a novel human atrial fibroblast cell line
por: Künzel, Stephan R., et al.
Publicado: (2020) -
Diminished PLK2 Induces Cardiac Fibrosis and Promotes Atrial Fibrillation
por: Künzel, Stephan R., et al.
Publicado: (2021)