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PARK7 promotes repair in early steroid-induced osteonecrosis of the femoral head by enhancing resistance to stress-induced apoptosis in bone marrow mesenchymal stem cells via regulation of the Nrf2 signaling pathway

Novel therapies for the treatment of early steroid-induced osteonecrosis of the femoral head (SONFH) are urgently needed in orthopedics. Transplantation of bone marrow mesenchymal stem cells (BMSCs) provides new strategies for treating this condition at the early stage. However, stress-induced apopt...

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Detalles Bibliográficos
Autores principales: Zhang, Fei, Yan, Yanglin, Peng, Wuxun, Wang, Lei, Wang, Tao, Xie, Zhihong, Luo, Hong, Zhang, Jian, Dong, Wentao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514492/
https://www.ncbi.nlm.nih.gov/pubmed/34645791
http://dx.doi.org/10.1038/s41419-021-04226-1