Prefused lysosomes cluster on autophagosomes regulated by VAMP8

Lysosome–autophagosome fusion is critical to autophagosome maturation. Although several proteins that regulate this fusion process have been identified, the prefusion architecture and its regulation remain unclear. Herein, we show that upon stimulation, multiple lysosomes form clusters around indivi...

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Detalles Bibliográficos
Autores principales: Chen, Qixin, Hao, Mingang, Wang, Lei, Li, Linsen, Chen, Yang, Shao, Xintian, Tian, Zhiqi, Pfuetzner, Richard A., Zhong, Qing, Brunger, Axel T., Guan, Jun-Lin, Diao, Jiajie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514493/
https://www.ncbi.nlm.nih.gov/pubmed/34645799
http://dx.doi.org/10.1038/s41419-021-04243-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514493/
https://www.ncbi.nlm.nih.gov/pubmed/34645799
http://dx.doi.org/10.1038/s41419-021-04243-0

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