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METTL3 improves cardiomyocyte proliferation upon myocardial infarction via upregulating miR-17-3p in a DGCR8-dependent manner

Myocardial infarction (MI), one of the most severe types of heart attack, exerts a strong negative effect on heart muscle by causing a massive and rapid loss of cardiomyocytes. However, the existing therapies do little to improve cardiac regeneration. Due to the role of methyltransferase-like 3 (MET...

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Detalles Bibliográficos
Autores principales: Zhao, Kun, Yang, Chuanxi, Zhang, Jing, Sun, Wei, Zhou, Bin, Kong, Xiangqing, Shi, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514505/
https://www.ncbi.nlm.nih.gov/pubmed/34645805
http://dx.doi.org/10.1038/s41420-021-00688-6