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METTL3 improves cardiomyocyte proliferation upon myocardial infarction via upregulating miR-17-3p in a DGCR8-dependent manner
Myocardial infarction (MI), one of the most severe types of heart attack, exerts a strong negative effect on heart muscle by causing a massive and rapid loss of cardiomyocytes. However, the existing therapies do little to improve cardiac regeneration. Due to the role of methyltransferase-like 3 (MET...
Autores principales: | Zhao, Kun, Yang, Chuanxi, Zhang, Jing, Sun, Wei, Zhou, Bin, Kong, Xiangqing, Shi, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514505/ https://www.ncbi.nlm.nih.gov/pubmed/34645805 http://dx.doi.org/10.1038/s41420-021-00688-6 |
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