Cargando…

m(6)A reader IGF2BP2-stabilized CASC9 accelerates glioblastoma aerobic glycolysis by enhancing HK2 mRNA stability

N(6)-methyladenosine (m(6)A) has been identified to exert critical roles in human cancer; however, the regulation of m(6)A modification on glioblastoma multiforme (GBM) and long non-coding RNA (lncRNA) CASC9 (cancer susceptibility 9) is still unclear. Firstly, MeRIP-Seq revealed the m(6)A profile in...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Hongjiang, Qin, Shan, Liu, Changqi, Jiang, Le, Li, Chen, Yang, Jiankai, Zhang, Shunyao, Yan, Zhongjie, Liu, Xiaopeng, Yang, Jipeng, Sun, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514511/
https://www.ncbi.nlm.nih.gov/pubmed/34645788
http://dx.doi.org/10.1038/s41420-021-00674-y