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Mitochondrial morphology is associated with respiratory chain uncoupling in autism spectrum disorder

Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is associated with unique changes in mitochondrial metabolism, including elevated respiration rates and morphological alterations. We examined electron transport chain (ETC) complex activity in fibroblasts derived from 18 children...

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Detalles Bibliográficos
Autores principales: Frye, Richard E., Lionnard, Loïc, Singh, Indrapal, Karim, Mohammad A., Chajra, Hanane, Frechet, Mathilde, Kissa, Karima, Racine, Victor, Ammanamanchi, Amrit, McCarty, Patrick John, Delhey, Leanna, Tippett, Marie, Rose, Shannon, Aouacheria, Abdel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514530/
https://www.ncbi.nlm.nih.gov/pubmed/34645790
http://dx.doi.org/10.1038/s41398-021-01647-6