Computer-aided engineering of a branching sucrase for the glucodiversification of a tetrasaccharide precursor of S. flexneri antigenic oligosaccharides

Enzyme engineering approaches have allowed to extend the collection of enzymatic tools available for synthetic purposes. However, controlling the regioselectivity of the reaction remains challenging, in particular when dealing with carbohydrates bearing numerous reactive hydroxyl groups as substrate...

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Detalles Bibliográficos
Autores principales: Benkoulouche, Mounir, Ben Imeddourene, Akli, Barel, Louis-Antoine, Lefebvre, Dorian, Fanuel, Mathieu, Rogniaux, Hélène, Ropartz, David, Barbe, Sophie, Guieysse, David, Mulard, Laurence A., Remaud-Siméon, Magali, Moulis, Claire, André, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514537/
https://www.ncbi.nlm.nih.gov/pubmed/34645865
http://dx.doi.org/10.1038/s41598-021-99384-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514537/
https://www.ncbi.nlm.nih.gov/pubmed/34645865
http://dx.doi.org/10.1038/s41598-021-99384-9

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