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TSSK4 upregulation in alveolar epithelial type-II cells facilitates pulmonary fibrosis through HSP90-AKT signaling restriction and AT-II apoptosis

Alveolar epithelial injury is one of the important pathological changes in idiopathic pulmonary interstitial fibrosis (IPF), but the regulatory mechanism remains unclear. Here, we reported that alveolar epithelial type-II cells (AT II) play important roles in pathological process of pulmonary fibros...

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Detalles Bibliográficos
Autores principales: Chen, Huifang, He, Andong, Li, Haoyang, Chen, Honglv, Xie, Huancheng, Luo, Liping, Huang, Yuyi, Chen, Jiaqian, Guan, Jieying, He, Qiaoling, Ma, Jianjuan, Ou, Changxing, Tao, Ailin, Yan, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514558/
https://www.ncbi.nlm.nih.gov/pubmed/34645797
http://dx.doi.org/10.1038/s41419-021-04232-3