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Protease-Activated Receptor-1 Antagonist Protects Against Lung Ischemia/Reperfusion Injury

Protease-activated receptor (PAR)-1 is a thrombin-activated receptor that plays an essential role in ischemia/reperfusion (IR)-induced acute inflammation. PAR-1 antagonists have been shown to alleviate injuries in various IR models. However, the effect of PAR-1 antagonists on IR-induced acute lung i...

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Detalles Bibliográficos
Autores principales: Chu, Shi-Jye, Tang, Shih-En, Pao, Hsin-Ping, Wu, Shu-Yu, Liao, Wen-I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514687/
https://www.ncbi.nlm.nih.gov/pubmed/34658893
http://dx.doi.org/10.3389/fphar.2021.752507