Death Receptors DR4 and DR5 Undergo Spontaneous and Ligand-Mediated Endocytosis and Recycling Regardless of the Sensitivity of Cancer Cells to TRAIL

Tumor necrosis factor-associated ligand inducing apoptosis (TRAIL) induces apoptosis through the death receptors (DRs) 4 and 5 expressed on the cell surface. Upon ligand stimulation, death receptors are rapidly internalized through clathrin-dependent and -independent mechanisms. However, there have...

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Detalles Bibliográficos
Autores principales: Artykov, Artem A., Yagolovich, Anne V., Dolgikh, Dmitry A., Kirpichnikov, Mikhail P., Trushina, Daria B., Gasparian, Marine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514705/
https://www.ncbi.nlm.nih.gov/pubmed/34660590
http://dx.doi.org/10.3389/fcell.2021.733688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514705/
https://www.ncbi.nlm.nih.gov/pubmed/34660590
http://dx.doi.org/10.3389/fcell.2021.733688

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