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Novel Combination of Surface Markers for the Reliable and Comprehensive Identification of Human Thymic Epithelial Cells by Flow Cytometry: Quantitation and Transcriptional Characterization of Thymic Stroma in a Pediatric Cohort

Thymic epithelial cells (TECs) are essential in supporting the development of mature T cells from hematopoietic progenitor cells and facilitate their lineage-commitment, proliferation, T-cell receptor repertoire selection and maturation. While animal model systems have greatly aided in elucidating t...

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Detalles Bibliográficos
Autores principales: Haunerdinger, Veronika, Moccia, Maria Domenica, Opitz, Lennart, Vavassori, Stefano, Dave, Hitendu, Hauri-Hohl, Mathias M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514761/
https://www.ncbi.nlm.nih.gov/pubmed/34659232
http://dx.doi.org/10.3389/fimmu.2021.740047