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Novel Combination of Surface Markers for the Reliable and Comprehensive Identification of Human Thymic Epithelial Cells by Flow Cytometry: Quantitation and Transcriptional Characterization of Thymic Stroma in a Pediatric Cohort
Thymic epithelial cells (TECs) are essential in supporting the development of mature T cells from hematopoietic progenitor cells and facilitate their lineage-commitment, proliferation, T-cell receptor repertoire selection and maturation. While animal model systems have greatly aided in elucidating t...
Autores principales: | Haunerdinger, Veronika, Moccia, Maria Domenica, Opitz, Lennart, Vavassori, Stefano, Dave, Hitendu, Hauri-Hohl, Mathias M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514761/ https://www.ncbi.nlm.nih.gov/pubmed/34659232 http://dx.doi.org/10.3389/fimmu.2021.740047 |
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