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Immune checkpoint deficiencies and autoimmune lymphoproliferative syndromes

Autoimmune lymphoproliferative syndrome (ALPS) is an inherited non-malignant and non-infectious lymphoproliferative syndrome caused by mutations in genes affecting the extrinsic apoptotic pathway (FAS, FASL, CASP10). The resulting FAS-mediated apoptosis defect accounts for the expansion and accumula...

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Detalles Bibliográficos
Autores principales: Gámez-Díaz, Laura, Grimbacher, Bodo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chang Gung University 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514790/
https://www.ncbi.nlm.nih.gov/pubmed/34384744
http://dx.doi.org/10.1016/j.bj.2021.04.005