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Immune checkpoint deficiencies and autoimmune lymphoproliferative syndromes
Autoimmune lymphoproliferative syndrome (ALPS) is an inherited non-malignant and non-infectious lymphoproliferative syndrome caused by mutations in genes affecting the extrinsic apoptotic pathway (FAS, FASL, CASP10). The resulting FAS-mediated apoptosis defect accounts for the expansion and accumula...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Chang Gung University
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514790/ https://www.ncbi.nlm.nih.gov/pubmed/34384744 http://dx.doi.org/10.1016/j.bj.2021.04.005 |