Germline STAT3 gain-of-function mutations in primary immunodeficiency: Impact on the cellular and clinical phenotype

Signal transducer and activator of transcription 3 (STAT3) is a key transcription factor involved in regulation of immune cell activation and differentiation. Recent discoveries highlight the role of germline activating STAT3 mutations in inborn errors of immunity characterized by early-onset multi-...

Descripción completa

Detalles Bibliográficos
Autores principales: Faletti, Laura, Ehl, Stephan, Heeg, Maximilian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chang Gung University 2021
Materias:
Review Article: Special Edition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514798/
https://www.ncbi.nlm.nih.gov/pubmed/34366294
http://dx.doi.org/10.1016/j.bj.2021.03.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514798/
https://www.ncbi.nlm.nih.gov/pubmed/34366294
http://dx.doi.org/10.1016/j.bj.2021.03.003

Ejemplares similares