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Heterogeneity of magnitude, allergen immunodominance, and cytokine polarization of cockroach allergen‐specific T cell responses in allergic sensitized children

BACKGROUND: Characterization of allergic responses to cockroach (CR), a common aeroallergen associated with asthma, has focused mainly on IgE reactivity, but little is known about T cell responses, particularly in children. We conducted a functional evaluation of CR allergen‐specific T cell reactivi...

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Detalles Bibliográficos
Autores principales: da Silva Antunes, Ricardo, Sutherland, Aaron, Frazier, April, Schulten, Veronique, Pomés, Anna, Glesner, Jill, Calatroni, Agustin, Altman, Matthew C., Wood, Robert A., O'Connor, George T., Pongracic, Jacqueline A., Khurana Hershey, Gurjit K., Kercsmar, Carolyn M., Gruchalla, Rebecca S., Gill, Michelle, Liu, Andrew H., Zoratti, Edward, Kattan, Meyer, Busse, Paula J., Bacharier, Leonard B., Teach, Stephen J., Wheatley, Lisa M., Togias, Alkis, Busse, William W., Jackson, Daniel J., Sette, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514843/
https://www.ncbi.nlm.nih.gov/pubmed/34691392
http://dx.doi.org/10.1002/clt2.12073