MicroRNA-195-5p Downregulation Inhibits Endothelial Mesenchymal Transition and Myocardial Fibrosis in Diabetic Cardiomyopathy by Targeting Smad7 and Inhibiting Transforming Growth Factor Beta 1-Smads-Snail Pathway

Diabetic cardiomyopathy (DCM) is a complication of diabetes mellitus, which is associated with fibrosis and microRNAs (miRs). This study estimated the mechanism of miR-195-5p in endothelial mesenchymal transition (EndMT) and myocardial fibrosis in DCM. After the establishment of DCM rat models, miR-...

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Detalles Bibliográficos
Autores principales: Ding, Huaisheng, Yao, Jianhui, Xie, Hongxiang, Wang, Chengyu, Chen, Jing, Wei, Kaiyong, Ji, Yangyang, Liu, Lihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514870/
https://www.ncbi.nlm.nih.gov/pubmed/34658906
http://dx.doi.org/10.3389/fphys.2021.709123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514870/
https://www.ncbi.nlm.nih.gov/pubmed/34658906
http://dx.doi.org/10.3389/fphys.2021.709123

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