Lack of IRF6 Disrupts Human Epithelial Homeostasis by Altering Colony Morphology, Migration Pattern, and Differentiation Potential of Keratinocytes

Variants within the gene encoding for the transcription factor Interferon Regulatory Factor 6 (IRF6) are associated with syndromic and non-syndromic Cleft Lip/Palate (CLP) cases. IRF6 plays a vital role in the regulation of the proliferation/differentiation balance in keratinocytes and is involved i...

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Detalles Bibliográficos
Autores principales: Girousi, Eleftheria, Muerner, Lukas, Parisi, Ludovica, Rihs, Silvia, von Gunten, Stephan, Katsaros, Christos, Degen, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514984/
https://www.ncbi.nlm.nih.gov/pubmed/34660580
http://dx.doi.org/10.3389/fcell.2021.718066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514984/
https://www.ncbi.nlm.nih.gov/pubmed/34660580
http://dx.doi.org/10.3389/fcell.2021.718066

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