Cargando…

Lack of IRF6 Disrupts Human Epithelial Homeostasis by Altering Colony Morphology, Migration Pattern, and Differentiation Potential of Keratinocytes

Variants within the gene encoding for the transcription factor Interferon Regulatory Factor 6 (IRF6) are associated with syndromic and non-syndromic Cleft Lip/Palate (CLP) cases. IRF6 plays a vital role in the regulation of the proliferation/differentiation balance in keratinocytes and is involved i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Girousi, Eleftheria, Muerner, Lukas, Parisi, Ludovica, Rihs, Silvia, von Gunten, Stephan, Katsaros, Christos, Degen, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514984/ https://www.ncbi.nlm.nih.gov/pubmed/34660580 http://dx.doi.org/10.3389/fcell.2021.718066

Ejemplares similares

A Novel Van der Woude Syndrome-Causing IRF6 Variant Is Subject to Incomplete Non-sense-Mediated mRNA Decay Affecting the Phenotype of Keratinocytes
por: Degen, Martin, et al.
Publicado: (2020)

A Living Cell Repository of the Cranio-/Orofacial Region to Advance Research and Promote Personalized Medicine
por: Parisi, Ludovica, et al.
Publicado: (2021)

Consistent downregulation of the cleft lip/palate-associated genes IRF6 and GRHL3 in carcinomas
por: Parisi, Ludovica, et al.
Publicado: (2022)

Discovery and characterization of heterogeneous and multipotent fibroblast populations isolated from excised cleft lip tissue
por: Parisi, Ludovica, et al.
Publicado: (2022)

Keratin 17 Is Required for Lipid Metabolism in Keratinocytes and Benefits Epidermal Permeability Barrier Homeostasis
por: Pang, Bingyu, et al.
Publicado: (2022)

Caffeine Targets G6PDH to Disrupt Redox Homeostasis and Inhibit Renal Cell Carcinoma Proliferation
por: Xu, Huanhuan, et al.
Publicado: (2020)

JMJD6 Dysfunction Due to Iron Deficiency in Preeclampsia Disrupts Fibronectin Homeostasis Resulting in Diminished Trophoblast Migration
por: Alahari, Sruthi, et al.
Publicado: (2021)

Biallelic Mutations in ACACA Cause a Disruption in Lipid Homeostasis That Is Associated With Global Developmental Delay, Microcephaly, and Dysmorphic Facial Features
por: Lou, Xiaoting, et al.
Publicado: (2021)

The Transcriptional Co-factor IRF2BP2: A New Player in Tumor Development and Microenvironment
por: Pastor, Tatiane P., et al.
Publicado: (2021)

Addressing Differentiation in Live Human Keratinocytes by Assessment of Membrane Packing Order
por: Gutowska-Owsiak, Danuta, et al.
Publicado: (2020)

Circular RNA circ0007360 Attenuates Gastric Cancer Progression by Altering the miR-762/IRF7 Axis
por: Xing, Yawei, et al.
Publicado: (2022)

Keratinocytes Isolated From Individual Cleft Lip/Palate Patients Display Variations in Their Differentiation Potential in vitro
por: Degen, Martin, et al.
Publicado: (2018)

Effect of cold atmospheric microwave plasma (CAMP) on wound healing in canine keratinocytes
por: Lertpatipanpong, Pattawika, et al.
Publicado: (2023)

Spatial Cell Disparity in the Colonial Choanoflagellate Salpingoeca rosetta
por: Naumann, Benjamin, et al.
Publicado: (2019)

DJ-1 Regulates Microglial Polarization Through P62-Mediated TRAF6/IRF5 Signaling in Cerebral Ischemia-Reperfusion
por: Wang, Tingting, et al.
Publicado: (2020)

Knockdown of FOXA2 Impairs Hair-Inductive Activity of Cultured Human Follicular Keratinocytes
por: Bak, Soon-Sun, et al.
Publicado: (2020)

Lack of Adiponectin Drives Hyperosteoclastogenesis in Lipoatrophic Mice
por: Madel, Maria-Bernadette, et al.
Publicado: (2021)

Lack of FAM20A, Ectopic Gingival Mineralization and Chondro/Osteogenic Modifications in Enamel Renal Syndrome
por: Simancas Escorcia, Victor, et al.
Publicado: (2020)

Neuronal cilia in energy homeostasis
por: Brewer, Kathryn M., et al.
Publicado: (2022)

Protein homeostasis in aging and cancer
por: Chen, Xiao-Qiong, et al.
Publicado: (2023)

Islet cilia and glucose homeostasis
por: Melena, Isabella, et al.
Publicado: (2022)

SUMO control of centromere homeostasis
por: van den Berg, Sebastiaan J. W., et al.
Publicado: (2023)

Characterization of multitype colonies originating from porcine blastocysts produced in vitro
por: Oh, Jong-Nam, et al.
Publicado: (2022)

Inhibition of Calcineurin/NFAT Signaling Blocks Oncogenic H-Ras Induced Autophagy in Primary Human Keratinocytes
por: Wang, Shuangshuang, et al.
Publicado: (2021)

Mitophagy, Mitochondrial Homeostasis, and Cell Fate
por: Ma, Kaili, et al.
Publicado: (2020)

Autophagy in the Regulation of Tissue Differentiation and Homeostasis
por: Perrotta, Cristiana, et al.
Publicado: (2020)

Tissue Tregs and Maintenance of Tissue Homeostasis
por: Shao, Qing, et al.
Publicado: (2021)

The Expression and Possible Functions of Tenascin-W During Development and Disease
por: Tucker, Richard P., et al.
Publicado: (2019)

Mechanotranduction Pathways in the Regulation of Mitochondrial Homeostasis in Cardiomyocytes
por: Liao, Hongyu, et al.
Publicado: (2021)

Editorial: Stem Cells in Tissue Homeostasis and Disease
por: Zhang, Wencheng, et al.
Publicado: (2022)

Regulation of Heme Synthesis by Mitochondrial Homeostasis Proteins
por: Yien, Yvette Y., et al.
Publicado: (2022)

Editorial: Protein homeostasis in growth, development and disease
por: Masciarelli, Silvia, et al.
Publicado: (2023)

Role of amino acid metabolism in mitochondrial homeostasis
por: Li, Qiaochu, et al.
Publicado: (2023)

Extracellular vesicles: an emerging player in retinal homeostasis
por: Chatterjee, Amit, et al.
Publicado: (2023)

The Granulocyte-colony stimulating factor has a dual role in neuronal and vascular plasticity
por: Wallner, Stephanie, et al.
Publicado: (2015)

Tranilast Directly Targets NLRP3 to Protect Melanocytes From Keratinocyte-Derived IL-1β Under Oxidative Stress
por: Zhuang, Tongtian, et al.
Publicado: (2020)

Border Security: The Role of RIPK3 in Epithelium Homeostasis
por: Moriwaki, Kenta, et al.
Publicado: (2016)

Migrasome and Tetraspanins in Vascular Homeostasis: Concept, Present, and Future
por: Zhang, Yaxing, et al.
Publicado: (2020)

RAMP2-AS1 Regulates Endothelial Homeostasis and Aging
por: Lai, Chih-Hung, et al.
Publicado: (2021)

ER-Phagy: A New Regulator of ER Homeostasis
por: Yang, Ming, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ehtup7pk3k9p3d4c4qjjkd330r