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Sodium Acetate Inhibit TGF-β1-Induced Activation of Hepatic Stellate Cells by Restoring AMPK or c-Jun Signaling

Short-chain fatty acids (SCFAs) are crucial gut microbial metabolites that play a major role in the occurrence and development of hepatic fibrosis (HF). However, the effect of SCFAs on hepatic stellate cells (HSCs), the major pro-fibrogenic cells, is yet undefined. In this study, the effects of thre...

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Detalles Bibliográficos
Autores principales: Li, Weiwei, Deng, Mingjuan, Gong, Jiahui, Zhang, Xiaoying, Ge, Shaoyang, Zhao, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515000/
https://www.ncbi.nlm.nih.gov/pubmed/34660662
http://dx.doi.org/10.3389/fnut.2021.729583