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Human and preclinical studies of the host–gut microbiome co-metabolite hippurate as a marker and mediator of metabolic health

OBJECTIVE: Gut microbial products are involved in regulation of host metabolism. In human and experimental studies, we explored the potential role of hippurate, a hepatic phase 2 conjugation product of microbial benzoate, as a marker and mediator of metabolic health. DESIGN: In 271 middle-aged non-d...

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Detalles Bibliográficos
Autores principales: Brial, François, Chilloux, Julien, Nielsen, Trine, Vieira-Silva, Sara, Falony, Gwen, Andrikopoulos, Petros, Olanipekun, Michael, Hoyles, Lesley, Djouadi, Fatima, Neves, Ana L, Rodriguez-Martinez, Andrea, Mouawad, Ghiwa Ishac, Pons, Nicolas, Forslund, Sofia, Le-chatelier, Emmanuelle, Le Lay, Aurélie, Nicholson, Jeremy, Hansen, Torben, Hyötyläinen, Tuulia, Clément, Karine, Oresic, Matej, Bork, Peer, Ehrlich, Stanislav Dusko, Raes, Jeroen, Pedersen, Oluf Borbye, Gauguier, Dominique, Dumas, Marc-Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515120/
https://www.ncbi.nlm.nih.gov/pubmed/33975870
http://dx.doi.org/10.1136/gutjnl-2020-323314