Teriflunomide Promotes Oligodendroglial 8,9-Unsaturated Sterol Accumulation and CNS Remyelination

BACKGROUND AND OBJECTIVES: To test whether low concentrations of teriflunomide (TF) could promote remyelination, we investigate the effect of TF on oligodendrocyte in culture and on remyelination in vivo in 2 demyelinating models. METHODS: The effect of TF on oligodendrocyte precursor cell (OPC) pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Martin, Elodie, Aigrot, Marie-Stephane, Lamari, Foudil, Bachelin, Corinne, Lubetzki, Catherine, Oumesmar, Brahim Nait, Zalc, Bernard, Stankoff, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515201/
https://www.ncbi.nlm.nih.gov/pubmed/34642237
http://dx.doi.org/10.1212/NXI.0000000000001091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515201/
https://www.ncbi.nlm.nih.gov/pubmed/34642237
http://dx.doi.org/10.1212/NXI.0000000000001091

Ejemplares similares