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Revealing the Timeline of Structural MRI Changes in Premanifest to Manifest Huntington Disease

BACKGROUND AND OBJECTIVES: Longitudinal measurements of brain atrophy using structural MRI (sMRI) can provide powerful markers for tracking disease progression in neurodegenerative diseases. In this study, we use a disease progression model to learn individual-level disease times and hence reveal a...

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Detalles Bibliográficos
Autores principales: Wijeratne, Peter A., Garbarino, Sara, Gregory, Sarah, Johnson, Eileanoir B., Scahill, Rachael I., Paulsen, Jane S., Tabrizi, Sarah J., Lorenzi, Marco, Alexander, Daniel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515202/
https://www.ncbi.nlm.nih.gov/pubmed/34660889
http://dx.doi.org/10.1212/NXG.0000000000000617