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Brain atrophy trajectories predict differential functional performance in Alzheimer's disease: Moderations with apolipoprotein E and sex

INTRODUCTION: We examine whether distinct brain atrophy patterns (using brain parenchymal fraction [BPF]) differentially predict functional performance and decline in Alzheimer's disease (AD), and are independently moderated by (1) a key AD genetic risk marker (apolipoprotein E [APOE]), (2) sex...

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Detalles Bibliográficos
Autores principales: Sapkota, Shraddha, Ramirez, Joel, Yhap, Vanessa, Masellis, Mario, Black, Sandra E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515221/
https://www.ncbi.nlm.nih.gov/pubmed/34692981
http://dx.doi.org/10.1002/dad2.12244